Alexandrina-Mihaela Dimofte, Doriana Agop Forna, Victor-Vlad Costan, Eugenia Popescu
Aim of the study To determine the effect of platelet-rich fibrin (PRF) on hard tissue healing following tooth extraction. Material and methods The study included 63 patients and a total of 183 extractions were performed. The study had a split-mouth design. Each patient had a study side where the sockets were filled with PRF and a control side, where the postextractional sockets underwent natural healing, by clot formation. After 3 months, for the evaluation of hard tissue quality, a bone density measurement was done using a Cone Bean Computer Tomogram (CBCT). Results Statistical analysis revealed a significant increase in bone density in the postextractional sockets where PRF was used as filling material. Conclusions It can be concluded that through the use of PRF as an augmentation material after tooth extraction the hard tissue healing process is significantly enhanced.
Key words: Platelet Rich Fibrin, Bone regeneration, Tooth Extraction