Romanian Journal of Oral Rehabilitation Numarul 2 ORAL MANIFESTATIONS OF IMMUNE THROMBOCYTOPENIA IN CHILDREN

ORAL MANIFESTATIONS OF IMMUNE THROMBOCYTOPENIA IN CHILDREN

Vasile Eduard Roşu, E. L. Spoială, T. S. Roşu, A. V. Ivanov, G. Scurtu, E. Tarca, I. C.Miron, C. Gavrilovici

ABSRACT

Immune thrombocytopenia in children is defined by a decrease in platelet counts < 100 x 109/L. The incidence of the disease varies from 1.6-6 per 100,000 children. Oral hemorrhagic manifestations (petechiae, epistaxis, gingivorrhagia, soft and hard palate hemorrhagic blisters) may be the first manifestations of the disease. Age over 1 year at diagnosis and the sudden onset of the symptom are the most important predictors of chronic disease. Oral hemorrhagic manifestations in ITP (immune thrombocytopenic purpura) in children are a warning sign in the evolution of the disease and a therapeutic challenge. Corticosteroid therapy and IV immunoglobulin, are  the first therapeutic line to follow. A multidisciplinary approach is a necessity for the proper management of the child with ITP.

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