When reporting experiments on human subjects, authors should indicate whether the procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1975, as revised in 2008, which is available at: http://www.healthscience.net/resources/declaration-of-helsinki/. If doubt exists whether the research was conducted in accordance with the Helsinki Declaration, the authors must explain the rationale for their approach and demonstrate that the institutional review body explicitly approved the doubtful aspects of the study.
When reporting experiments on animals, authors should indicate whether the institutional and national guide for the care and use of laboratory animals was followed. The materials and methods (experimental procedures) section must clearly indicate that appropriate measures were taken to minimize pain or discomfort, and details of animal care should be provided.
Informed Consent- Study Participants-
1. Authors should not include identifying patient information, including patients’ names, initials, or hospital numbers, in written descriptions, photographs, and pedigrees unless the information is essential for scientific purposes and the patient (or parent/ guardian) gives written, informed consent for publication.
2. Complete anonymity is difficult to achieve; however, informed consent should be obtained if there is any doubt. For example, masking the eye region in photographs of patients is inadequate protection of anonymity.
3. When informed consent has been obtained, it should be indicated in the published article and a copy of the ‘Patient Informed Consent Form’ for each patient should be included along with article submission.
4. Authors should provide written verification that any study participants who are identifiable have been shown the final manuscript to be published.
5. Masked Study Participants- If identifying characteristics are altered to protect anonymity, such as in genetic malformations, authors should provide written assurance to the editors that alterations do not distort scientific meaning.