Alexandra Diaconu, Octavian Dinca, Cristina Padurariu, Mihai Bogdan Bucur, Cristina Padurariu ,Cristian Vladan , Alexandru Bucur


Aim of the study The aim of this study is to compare glycemic variability of 2% plain lidocaine to 4% articaine with epinephrine 1:200,000 during tooth extraction. Material and methods This prospective study was carried out in 60 diabetes melitus patients who presented at the Clinic of Oral and Maxillofacial Surgery, Carol Davila  University, OMFS Hospital, Bucharest, from 2019 to 2020 for tooth extraction. Patients were randomly allocated to two groups (30 patients in each group) according to the type of anaesthetic solution employed. Group 1 had tooth extraction done under 4% articaine with 1:200,000 epinephrine while group 2 had tooth extraction done under plain 2% lidocaine. One tooth was extracted from each patient. Blood glucose level was  recorded before surgery, after local anaesthetic injection and one hour after the administration of anesthetic agent. Results There was no statistically significant difference between the glycemic response in the two groups after administration of regional block anaesthesia. However the highest alteration in parameters was observed one hour after procedure in the two groups. Conclusions The glycemic changes induced by injecting 4% articaine with epinephrine in patients with controlled diabetes melitus during tooth extraction is within normal range and is not different from that induced by plain 2% lidocaine. The general preference given to local anesthetics without vasoconstrictor in diabetics is not supported by the present study

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