Ciofu Mihai Liviu, Andrada Raluca Doscas, Andrei Nicolau, Christina Ungureanu, Daniel Timofte
Aim of the study The aim of this study is to present the development of brown tumors in the jaws as a consequence of secondary hyperparathyroidism (HPT). Material and methods We analysed 10 cases with brown tumor of the jaws developed in patients with HPT which presented in our Oral and Maxillofacial Clinic for evaluation and treatment of their disease. The patients were 7 females and 3 males, with ages between 13 and 58 years. Results All patients were symptomatic and bone deformation was noted in all cases. The mandible was involved in 5 patients, the maxillary bone in 4 cases and in one case the tumor was localized in both jaws. The PTH values ranged from 630 pg/ml to 2500 pg/ml. All patients were referred for parathyroidectomy and for 2 patients, local excision was performed. Conclusions Regression of brown tumors may be achieved by performing parathyroidectomy. Multidisciplinary follow-up is essential for the control of brown tumors in order to prevent rapid growth which may lead to severe deformities and functional alterations.
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