Alina Mihaela Elisei, Corina Cecilia Manole Palivan, Gabi Topor, Elisabeta Marinescu, Anamaria Zaharescu, Dumitriu Olimpia Buzia, Kamel Earar, Ovidiu Schipor
Chlorhexidine (CHX) is one of the most widely used antiseptic. Chlorhexidine plays a key role in the dentistry and has earned its eponym of the gold standard. Available as mouthwash, gel, aerosol, spray and disks, CHX is considered a safe compound, with minimal and transitory local and systemic side effects. Its antimicrobial effects persist because it is binds strongly to proteins in the skin and mucosa, making it an effective antiseptic ingredient for handwashing, skin preparation for surgery and the placement of intravascular access. This review discusses the aspects regarding the characteristics, the formulations and problems associated with the use of chlorhexidine.