Particularities Of Chemical Gastritis In Children

Gabriela Paduraru, Marin Burlea, Valeriu V. Lupu, Smaranda Diaconescu

Objectives: The authors intend to show correlations between the clinical, endoscopic and echographic aspects of the chemical gastritis and the infection with Helicobacter Pylori. Materials and methods: A lot of 298 patients hospitalized in the 5th Clinic of Paediatrics of the „Sf. Maria” Emergency Children Hospital Iaşi during the period January 2008 – December 2010 was studied. The patients underwent upper digestive endoscopy, abdominal echography and esogastroduodenal transit. Results: The symptomatology was present in the majority of patients with epigastric pain, nausea, biliary vomiting. Anatomical changes of the gall bladder were echographically detected: septate cholecyst, hypotone, thickened walls. Macroscopic lesions of the gastric mucosa, especially of the antral region and large quantities of bile in stomach were endoscopically observed. Gastric biopsy was used to detect the presence of H. pylori. EGD transit has shown motility changes of the superior digestive tube in most patients. The treatment consisted in administration of gastric acidity inhibitors and ursodeoxicolic acid for 21 days. A positive response to this treatment was obtained for the majority of cases. Conclusions: The reflux gastritis is a new clinical and therapeutic entity in the paediatric practice, frequently occurring in anatomically normal stomach. The reflux gastritis can be associated with the HP infection and aggravates it clinically. It is also frequently correlated with anatomical anomalies of the gall bladder and changes in the digestive tract motility.

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