Emdogain And Bio-Oss Between Hope And Reality

Laura Cirligeriu, M. Boariu, A. Marinescu, V. Carligeriu

In the last years the treatment of periodontal disease has gain new meanings thanks to new developed materials that helped the surgical treatment. The developers of these materials promise a lot in the field of guided tissue regeneration, but in order to know how much of these is true we tried some of them in clinical tests. The most frequently used materials by us was Emdogain and Bio-Oss and made a study (similar studies was conducted by Sculeanu et.al.) to demonstrate how much of these materials properties was hope and how much was reality. The aim of the study was to evaluate the clinical and radiographic outcome using two different materials in the treatment of periodontal bone defects based on guided tissue regeneration techniques (2). Our study included 40 subjects with generally healthy status with periodontitis ilness in advanced stage. Depending of the materials used in the treatment our patients were divided into two equal groups. The group number I, was treated with a bovine-derived hydroxyapatite xenograft (Bio-Oss, ) combined with a resorbable collagen membrane (COREM, Poneti) was used. In the second group was used enamel matrix derivative (Emdogain® Gel). Before the surgical treatment a clinical and radiographic examinations were performed, and the following parameters were evaluated: plaque index, gingival index, probing pocket depth, clinical attachment level, radiographic defect depth, and defect width. At the patients with bad oral hygiene the plaque and gingival index was haing high values. All clinical and radiographic parameters (except plaque index) were significantly reduced after treatment in both groups . No great differences were revealed between the two groups of patients in examined parameters after treatment. The results demonstrated that the treatment of periodontal bone defects with both materials leads to similar and significant improvements in clinical and radiographic parameters. The exception was made by the patients with bad oral hygiene.

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