A Rare Case of Infantile Grave’s Disease

Smaranda Diaconescu, Anamaria Burlea, V.V. Lupu, M.Glod

The authors presents a rare case of a 12 years-old girl with Grave’s disease with typical clinical features apearing after an emotional stress. After a first-line treatment with antithyroid drugs the thyrotoxic syndrome relapsed because the lack of compliance and side effects of this medication (carbimazole). Convenient preparation to achieve the euthyroid state allowed the young patient to support a near total thyroidectomy with immediate and long-term good result. Considerations about the pathways leading to Grave’s disease, clinical and bioumoral diagnosis and especially the indications, advantages and failures of the three main methods of therapy i.e. antithyroid drugs, ablative radioiodine and surgery are discussed.

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